1. Hardy Weinberg |
· Allele frequencies |
· p and q by counting alleles |
· genotype frequencies |
· Random sampling |
· Hardy Weinberg equation |
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2. Co-dominant Alleles |
· Determining p and q from population |
· Determining if population is in HWE |
· chi2 test |
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3. Marriages Between Populations |
· p and q in the two populations |
· Genotype frequencies in the progeny |
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4. Estimating Heterozygote Frequencies |
· Common recessive trait (non-taster for PTC) |
· Heterozygote frequency estimation |
· Heterozygote frequency among dominant phenotype class |
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5. X-linked Recessive |
· Genotype frequencies: male vs female |
· Proportion of marriages with particular outcomes |