Linkage
Problems:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1. Dihybrid cross (corn)
· Recessive alleles
· Linkage
· Recombination
· Cis arrangement
· Recombination frequency, map units
· Using F2 progeny ratios to determine map units
· Using map units to determine F2 progeny ratios
 
2. Dihybrid cross (FlyLab: forked and scalloped)
· X-linked recessives in cis
· Test cross vs sibling cross
· Recombinants and parentals
· Map distance
 
3. Dihybrid cross (FlyLab: forked and miniature)
· X-linked recessive
· Cis vs trans
· 3 two factor crosses to build map (forked, scalloped and miniature)
 
4. Dihybrid cross (FlyLab: spineless and incomplete)
· Autosomal recessives
· Test cross
· No recombination in males
 
5. Trihybrid cross (FlyLab: miniature, singed, tan)
· Gene order
· Genetic map
 
6. Dihybrid, trihibrid cross (mice)
· Autosomal dominant, autosomal recessive
· Genotypes
· Given map with three markers, predict number of F2 progeny